 Active
Ingredients: Garcinia Cambogia, apple cider vinegar,
powered cellulose
The primary active ingredient in Agel FIT is Super
CitriMax®. It is the patent pending form hydroxycitric
acid (HCA) which comes from the extract of the fruit and
rind of the Asian fruit called Garcinia Cambogia.
HCA has been shown in clinical trials to decrease body
weight by reducing appetite, inhibiting fat synthesis,
and increasing fat metabolism, without artificial
stimulation of the central nervous system. The HCA in
Super CitriMax® is bound to calcium and potassium, which
maximizes its solubility, thereby, increasing its
bioavailability. Research has shown that HCA potency,
bioavailability, timing of ingestion, and dosage are the
essential requirements for optimal results. In addition,
the safety of Super CitriMax® has been confirmed in
recently published studies.
HCA has been found to produce multiple physiological
effects. One of these effects is appetite suppression.
Recent clinical studies show that Super CitriMax®
increases levels of serotonin (5-HT) by blocking its
re-uptake in the brain. This neurotransmitter has been
found to play a vital role in a wide range of behavioral
functions in the body, including mood, sleep and
appetite control. Studies show that serotonin levels are
closely related to eating behavior and body weight.
There is a significant correlation between increased
plasma levels of serotonin and decreased food intake,
reduced weight gain and increased energy expenditure. In
addition to its effect on appetite, increased serotonin
levels may also play a beneficial role in helping
overweight people face some of the related emotional
issues, including binge-eating and depression.
HCA also inhibits the production of fatty acids by
inhibiting the biochemical action of a intra cellular
enzyme called ATP citrate lyase. ATP citrate lyase
controls the biosynthesis of cellular Acetyl CoA (a
carbohydrate-derived building block for fatty acids).
Acetyl CoA is originally synthesized in the cellular
mitochondria, but since the mitochondrial membrane is
impermeable to Acetyl CoA, it is converted into
hydroxycitrate, pumped across the mitochondrial membrane
then reconverted from hydroxycitrate into Acetyl CoA and
Oxaloacetate via ATP citrate lyase. However, in the
presence of adequate HCA, ATP citrate lyase is
deactivated, thereby blocking the synthesis of fatty
acids from carbohydrates and their subsequent storage in
the liver. This also prompts biochemical changes in the
liver that promote fat burning. By switching this enzyme
off, HCA effectively blocks the conversion of starch and
sugary foods into fat, and consequently, HCA is known as
a lipogenesis (lipo – fat, genesis – creation)
inhibitor. In other words, with Super CitriMax®, fatty
acid synthesis is switched off.
Super CitriMax® has also been found to have a beneficial
effect on cholesterol levels. In addition to helping
with weight management, Super CitriMax® has been found
to lower triglycerides, LDL (bad cholesterol) and
increase HDL (beneficial cholesterol).
There are many weight management products on the market
that use HCA as the active ingredient. However, most of
them do not use Super CitriMax.® This patent pending
form of HCA is bound to the minerals calcium and
potassium. Consequently, the HCA is virtually 100%
soluble, and therefore more bioavailable than regular
calcium-based HCA ingredients. Super CitriMax® also
contains 20% more HCA than ordinary HCA products. In its
new formulation, Super CitriMax® has been shown to be
significantly more effective as a weight management aid
than previous formulations of HCA.
Super CitriMax® in and of itself is a well-proven weight
management aid. However, now that it is formulated as an
integral part of Agel Fit, its true potential will be
realized.
Super CitriMax®
Tomita K, Okuhara Y, Shigematsu N, Suh
H, Lim K.
Biosci Biotechnol Biochem. 2003
Sep;67(9):1999-2001.
Ohia SE, Opere
CA, LeDay AM, Bagchi M, Bagchi D, Stohs
SJ.
Mol Cell Biochem. 2002
Sep;238(1-2):89-103.
Westerterp-Plantenga MS, Kovacs EM.
Int J Obes Relat Metab Disord. 2002
Jun;26(6):870-2.
For more information and references to scientific
studies and research, please visit
www.agel.com
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